National Cancer Institute Thesaurus

Last uploaded: December 30, 2019
Preferred Name

Adverse Event

Synonyms

AE

Adverse Experience

side effects

AdverseEvent

adverse event (AE)

adverse event

adverse experience

Adverse Event

ADVERSE EVENT

Definitions

Any unfavorable or unintended disease, sign, or symptom (including an abnormal laboratory finding) that is temporally associated with the use of a medical treatment or procedure, and that may or may not be considered related to the medical treatment or procedure. Such events can be related to the intervention, dose, route of administration, patient, or caused by an interaction with another drug(s) or procedure(s).

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C41331

ALT_DEFINITION

Any unfavorable and unintended sign, symptom, disease, or other medical occurrence with a temporal association with the use of a medical product, procedure or other therapy, or in conjunction with a research study, regardless of causal relationship. EXAMPLE(S): death, back pain, headache, pulmonary embolism, heart attack OTHER NAME(S): NOTE(S): The BRIDG SCC has a GForge Tracker Issue (#31893) indicating a need to validate the requirement that every AdverseEvent be described by a SafetyReportVersion.

Any untoward medical occurrence in a patient or clinical investigation subject administered a pharmaceutical product and which does not necessarily have a causal relationship with this treatment. An adverse event (AE) can therefore be any unintended sign (including an abnormal laboratory finding), symptom, or disease temporally associated with the use of a medicinal (investigational) product, whether or not related to the medicinal (investigational) product. NOTE: For further information, see the ICH Guideline for Clinical Safety Data Management: Definitions and Standards for Expedited Reporting. [Modified from ICH E2A] Synonyms: side effect, adverse experience. See also serious adverse event, serious adverse experience. (CDISC glossary)

Any unfavorable or unintended disease, sign, or symptom (including an abnormal laboratory finding) that is temporally associated with the use of a medical treatment or procedure, and that may or may not be considered related to the medical treatment or procedure. Such events can be related to the intervention, dose, route of administration, patient, or caused by an interaction with another drug(s) or procedure(s).

Any untoward medical occurrence in a patient or clinical investigation subject administered a pharmaceutical product and which does not necessarily have a causal relationship with this treatment. an adverse event (AE) can therefore be any unintended sign (including an abnormal laboratory finding), symptom, or disease temporally associated with the use of a medicinal (investigational) product, whether or not related to the medicinal (investigational) product. NOTE: For further information, see the ICH Guideline for Clinical safety Data Management: Definitions and standards for expedited Reporting. [After ICH E2A] See also serious adverse event, serious adverse experience.

Any unfavorable and unintended sign, symptom, disease, or other medical occurrence with a temporal association with the use of a medical product, procedure or other therapy, or in conjunction with a research study, regardless of causal relationship. EXAMPLE(S): death, back pain, headache, pulmonary embolism, heart attack

An unexpected medical problem that happens during treatment with a drug or other therapy. Adverse effects do not have to be caused by the drug or therapy, and they may be mild, moderate, or severe.

code

C41331

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C66830

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61410

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159503

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C67497

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C54447

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C159501

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C66727

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C54580

Contributing_Source

BRIDG

CDISC

FDA

CDISC-GLOSS

DEFINITION

Any unfavorable or unintended disease, sign, or symptom (including an abnormal laboratory finding) that is temporally associated with the use of a medical treatment or procedure, and that may or may not be considered related to the medical treatment or procedure. Such events can be related to the intervention, dose, route of administration, patient, or caused by an interaction with another drug(s) or procedure(s).

FULL_SYN

AE

Adverse Experience

side effects

AdverseEvent

adverse event (AE)

adverse event

adverse experience

Adverse Event

ADVERSE EVENT

label

Adverse Event

Legacy_Concept_Name

Adverse_Event

Preferred_Name

Adverse Event

prefixIRI

ncit:C41331

Semantic_Type

Finding

UMLS_CUI

C0877248

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C36291

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http://purl.bioontology.org/ontology/LNC/MTHU014542 LOINC LOOM
http://purl.bioontology.org/ontology/MEDDRA/10060933 NLN LOOM
http://purl.bioontology.org/ontology/MEDDRA/10060933 MEDDRA LOOM
http://www.semanticweb.org/ontologies/2012/0/Ontology1325521724189.owl#Adverse_Event_Sub-Domain CTO LOOM
http://purl.obolibrary.org/obo/MVC_0000510 MIXSCV LOOM
http://www.bridgmodel.org/owl#AdverseEvent BRIDG LOOM
http://www.semanticweb.org/ontologies/2012/0/Ontology1325521724189.owl#Adverse_events CTO LOOM
http://hl7.org/fhir/adverseEvent FASTO LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C41331 ROO LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C41331 ROO SAME_URI
http://purl.obolibrary.org/obo/AERO_0000009 AERO LOOM
http://doe-generated-ontology.com/OntoAD#C0877248 ONTOAD LOOM
http://purl.obolibrary.org/obo/OAE_0000001 ODNAE LOOM
http://purl.obolibrary.org/obo/OAE_0000001 ICO LOOM
http://purl.obolibrary.org/obo/OAE_0000001 GSSO LOOM
http://purl.obolibrary.org/obo/OAE_0000001 VO LOOM
http://purl.obolibrary.org/obo/OAE_0000001 GSSO LOOM
http://purl.obolibrary.org/obo/OAE_0000001 GSSO LOOM
http://purl.obolibrary.org/obo/OAE_0000001 ENM LOOM
http://purl.obolibrary.org/obo/OAE_0000001 OGSF LOOM
http://purl.obolibrary.org/obo/OAE_0000001 OCMR LOOM
http://purl.obolibrary.org/obo/OAE_0000001 GSSO LOOM
http://purl.obolibrary.org/obo/OAE_0000001 OPMI LOOM
http://purl.obolibrary.org/obo/OAE_0000001 GSSO LOOM
http://purl.obolibrary.org/obo/OAE_0000001 GSSO LOOM
http://purl.obolibrary.org/obo/OAE_0000001 ODAE LOOM
http://purl.obolibrary.org/obo/OAE_0000001 DINTO LOOM
http://purl.obolibrary.org/obo/OAE_0000001 GSSO LOOM
http://purl.obolibrary.org/obo/OAE_0000001 GSSO LOOM
http://purl.obolibrary.org/obo/OAE_0000001 GSSO LOOM
http://purl.obolibrary.org/obo/OAE_0000001 GSSO LOOM
http://purl.obolibrary.org/obo/OAE_0000001 OLAM LOOM
http://purl.obolibrary.org/obo/OAE_0000001 VICO LOOM
http://purl.obolibrary.org/obo/OAE_0000001 OPMI LOOM
http://purl.obolibrary.org/obo/OAE_0000001 VO LOOM
http://purl.obolibrary.org/obo/OAE_0000001 DIDEO LOOM
http://purl.obolibrary.org/obo/OAE_0000001 OCVDAE LOOM
http://purl.obolibrary.org/obo/OAE_0000001 OPMI LOOM
http://purl.obolibrary.org/obo/OAE_0000001 GSSO LOOM
http://purl.obolibrary.org/obo/OAE_0000001 GSSO LOOM
http://purl.obolibrary.org/obo/OAE_0000001 GSSO LOOM
http://purl.obolibrary.org/obo/OAE_0000001 GSSO LOOM
http://purl.obolibrary.org/obo/OAE_0000001 DMTO LOOM
http://purl.obolibrary.org/obo/OAE_0000001 OVAE LOOM
http://purl.obolibrary.org/obo/OAE_0000001 OAE LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#51845 OCHV LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0877248 OCHV LOOM
http://purl.jp/bio/4/id/201506015651149055 IOBC LOOM
http://purl.bioontology.org/ontology/CMDO/CM0504 CMDO LOOM
http://purl.bioontology.org/ontology/LNC/LA7266-5 LOINC LOOM